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Dynamics of immune escape during HIV/SIV infection.

Several studies have shown that cytotoxic T lymphocytes (CTLs) play an important role in controlling HIV/SIV infection. Notably, the observation of escape mutants suggests a selective pressure induced by the CTL response. However, it remains difficult to assess the definite role of the cellular immu...

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Detalles Bibliográficos
Autores principales: Christian L Althaus, Rob J De Boer
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2008-01-01
Colección:PLoS Computational Biology
Acceso en línea:http://europepmc.org/articles/PMC2423483?pdf=render
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