PTEN-Induced Putative Kinase 1 Dysfunction Accelerates Synucleinopathy
Background: Mutations in PTEN-induced putative kinase 1 ( PINK1 ) cause autosomal recessive Parkinson’s disease (PD) and contribute to the risk of sporadic PD. However, the relationship between PD-related PINK1 mutations and alpha-synuclein (α-syn) aggregation—a main pathological component of PD—rem...
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| Huvudupphov: | , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
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SAGE Publishing
2022-05-01
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| Serie: | Journal of Parkinson’s Disease |
| Länkar: | https://doi.org/10.3233/JPD-213065 |
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