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Modulation of Nrf2/HO-1 by Thymoquinone During Cisplatin-Induced Nephrotoxicity

OBJECTIVE: Side effects of cisplatin, such as nephrotoxicity, limit its use in chemotherapeutic regimens and indicate an agent that suppresses its toxicity. Thymoquinone (TQ), the predominant bioactive constituent present in black seed oil (Nigella sativa), has antiinfl ammatory, antioxidant and an...

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Autori principali: Ramazan ULU, Ayhan DOĞUKAN, Mehmet TUZCU, Ali GÜREL, Irfana MUQBİL, Ramzi M MOHAMMAD, Kazım ŞAHİN
Natura: Artigo
Lingua:Inglês
Pubblicazione: Turkish Society of Nephrology 2019-02-01
Serie:Turkish Journal of Nephrology
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Accesso online:https://turkjnephrol.org/index.php/pub/article/view/888
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