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Noninvasive prediction of BRAF V600E mutation status of pleomorphic xanthoastrocytomas with MRI morphologic features and diffusion-weighted imaging

Abstract Objectives Seeking a noninvasive predictor for BRAF V600E mutation status of pleomorphic xanthoastrocytomas (PXAs) is essential for their prognoses and therapeutic use of BRAF inhibitors. We aimed to noninvasively diagnose BRAF V600E-mutated PXAs using MRI morphologic, DWI and clinical para...

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Principais autores: Jing Yan, Cuiping Guo, Hongwei Zheng, Yinhua Li, Mengjiao Duan, Chaoli Zhang, Li Cui, Xiaofei Lv, Gui Fu, Jingliang Cheng
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-08-01
Serier:BMC Cancer
Fag:
Astrocytoma
Proto-oncogene proteins B-raf
Mutation
Magnetic resonance imaging
Diffusion
Online adgang:https://doi.org/10.1186/s12885-024-12713-9
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