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Altered effector function of peripheral cytotoxic cells in COPD

<p>Abstract</p> <p>Background</p> <p>There is mounting evidence that perforin and granzymes are important mediators in the lung destruction seen in COPD. We investigated the characteristics of the three main perforin and granzyme containing peripheral cells, namely CD8<sup>+ </sup>T lymphocytes, nat...

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Autors principals: Corne Jonathan M, Todd Ian, Lamb Jonathan R, Urbanowicz Richard A, Fairclough Lucy C
Format: Artigo
Idioma:Inglês
Publicat: BMC 2009-06-01
Col·lecció:Respiratory Research
Accés en línia:http://respiratory-research.com/content/10/1/53
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