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Mannosylated lipoarabinomannans from Mycobacterium avium subsp. paratuberculosis alters the inflammatory response by bovine macrophages and suppresses killing of Mycobacterium avium subsp. avium organisms.

Analysis of the mechanisms through which pathogenic mycobacteria interfere with macrophage activation and phagosome maturation have shown that engagement of specific membrane receptors with bacterial ligands is the initiating event. Mannosylated lipoarabinomannan (Man-LAM) has been identified as one...

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Библиографические подробности
Главные авторы: Cleverson Souza, William C Davis, Torsten M Eckstein, Srinand Sreevatsan, Douglas J Weiss
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2013-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC3786972?pdf=render
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