Topological signatures differentiating episodic and chronic phenotypes in migraine without aura: a multi-scale analysis revealing divergent network profiles

Abstract Background The differences between episodic and chronic migraine phenotypes imply a system-level network reorganization often obscured by traditional discrete analyses. We employed multidimensional functional gradient analysis to characterize these distinct topological patterns and anchor t...

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Bibliografiske detaljer

Principais autores:	Chenyu Lin, Chenyu Dai, Yixuan Hu, Xiaojie Zhang, Zi Tao, Xiaoqing Liu, Xinhao Li, Tong Xu, Mengqian Ye, Yungang Cao, Keyang Chen, Kun Liu, Xiaozheng Liu, Fangwang Fu, Yan Li
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2026-04-01
Serier:	The Journal of Headache and Pain
Fag:	Migraine without aura Functional connectome gradients Manifold topology Multi-scale analysis Transcriptomics
Online adgang:	https://doi.org/10.1186/s10194-026-02366-3
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