Overexpression of NUDT16L1 sustains proper function of mitochondria and leads to ferroptosis insensitivity in colorectal cancer

Cancer research is continuously exploring new avenues to improve treatments, and ferroptosis induction has emerged as a promising approach. However, the lack of comprehensive analysis of the ferroptosis sensitivity in different cancer types has limited its clinical application. Moreover, identifying...

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Hlavní autoři:	Yi-Syuan Lin, Ya-Chuan Tsai, Chia-Jung Li, Tzu-Tang Wei, Jui-Lin Wang, Bo-Wen Lin, Ya-Na Wu, Shang-Rung Wu, Shin-Chih Lin, Shih-Chieh Lin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-11-01
Edice:	Redox Biology
Témata:	Colon cancer Ferroptosis insensitivity NUDT16L1 Mitochondrial function Mitochondrial DNA leakage Tumor growth
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2213231724003367
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