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Blockade of IL-36 receptor signaling does not prevent from TNF-induced arthritis.

<h4>Introduction</h4>Interleukin (IL)-36α is a newly described member of the IL-1 cytokine family with a known inflammatory and pathogenic function in psoriasis. Recently, we could demonstrate that the receptor (IL-36R), its ligand IL-36α and its antagonist IL-36Ra are expressed in synovial tissue o...

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Autors principals: Anja Derer, Bettina Groetsch, Ulrike Harre, Christina Böhm, Jennifer Towne, Georg Schett, Silke Frey, Axel J Hueber
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2014-01-01
Col·lecció:PLoS ONE
Accés en línia:https://doi.org/10.1371/journal.pone.0101954
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