Brazilin is a natural product inhibitor of the NLRP3 inflammasome

Summary: Excessive or aberrant NLRP3 inflammasome activation has been implicated in the progression and initiation of many inflammatory conditions; however, currently no NLRP3 inflammasome inhibitors have been approved for therapeutic use in the clinic. Here we have identified that the natural produ...

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التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Emily McMahon, Sherihan El-Sayed, Jack Green, Christopher Hoyle, Lorna FitzPatrick, Emma V. Jones, Eve Corrie, Rebecca L. Kelly, Mairi Challinor, Sally Freeman, Richard A. Bryce, Catherine B. Lawrence, David Brough, Paul R. Kasher
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Elsevier 2024-02-01
سلاسل:	iScience
الموضوعات:	Biological sciences Biochemistry Biomolecules Natural product biochemistry
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2589004224001895
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!