Allantoin ameliorates chemically-induced pancreatic β-cell damage through activation of the imidazoline I3 receptors

Objective. Allantoin is the primary active compound in yams (Dioscorea spp.). Recently, allantoin has been demonstrated to activate imidazoline 3 (I3) receptors located in pancreatic tissues. Thus, the present study aimed to investigate the role of allantoin in the effect to improve damage induced i...

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Principais autores:	Marie Amitani, Kai-Chun Cheng, Akihiro Asakawa, Haruka Amitani, Timothy Sean Kairupan, Nanami Sameshima, Toshiaki Shimizu, Teruto Hashiguchi, Akio Inui
Formato:	Artigo
Idioma:	Inglês
Publicado:	PeerJ Inc. 2015-08-01
Series:	PeerJ
Assuntos:	Allantoin Imidazoline 3 receptor Pancreatic PLC-related pathway Streptozotocin
Acceso en liña:	https://peerj.com/articles/1105.pdf
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