Sirtuin 3 Dependent and Independent Effects of NAD⁺ to Suppress Vascular Inflammation and Improve Endothelial Function in Mice

Atherosclerosis is initiated by endothelial cell dysfunction and vascular inflammation under the condition of hyperlipidemia. Sirtuin 3 (SIRT3) is a nicotinamide adenine dinucleotide (NAD⁺)-dependent mitochondrial deacetylase, which plays a key role in maintaining normal mitochondrial fun...

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Bibliografische gegevens

Hoofdauteurs:	Xiaoyun Cao, Yalan Wu, Huiling Hong, Xiao Yu Tian
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2022-04-01
Reeks:	Antioxidants
Onderwerpen:	atherosclerosis vascular inflammation endothelial dysfunction mitochondrial ROS sirtuins
Online toegang:	https://www.mdpi.com/2076-3921/11/4/706
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