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Non-polar components in PM2.5 increase matrix remodeling of CRS by up-regulating CEMIP in nasal fibroblasts

BackgroundFine particulate matter (PM2.5) is harmful to respiratory health and can lead to chronic rhinosinusitis (CRS). But how its components lead to CRS by affecting the function of nasal fibroblasts remains unclear.MethodsIn this study, polar organic components (P-OC) and non-polar organic compo...

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Hoofdauteurs: Jiayao Zhou, Ying Zhu, Huilin Hu, Ru Tang, Shiyao Zhang, Yuelong Gu, Song Mao, Shilei Pu, Hai Lin, Yue Zhao, Zhipeng Li, Weitian Zhang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2025-10-01
Reeks:Frontiers in Genetics
Onderwerpen:
fine particulate matter
organic components
chronic rhinosinusitis
fibroblast
cell migration inducing hyaluronidase 1
Online toegang:https://www.frontiersin.org/articles/10.3389/fgene.2025.1672729/full
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