Machine learning estimation of FVIII pharmacokinetic parameters in Chinese children with severe Hemophilia A
Abstract Hemophilia A is a rare inherited bleeding disorder typically managed with coagulation factor VIII (FVIII) replacement therapy. Designing personalized prophylactic regimens requires accurate pharmacokinetic (PK) characterization; current population PK (popPK) and Bayesian approaches provide...
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| Principais autores: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2026-02-01
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| coleção: | npj Systems Biology and Applications |
| Acesso em linha: | https://doi.org/10.1038/s41540-026-00674-7 |
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