Transcriptome analysis of the aged SAMP8 mouse model of Alzheimer’s disease reveals novel molecular targets of formononetin protection

BackgroundSenescence-accelerated mouse prone 8 (SAMP8) and age-matched SAMR1 mice are used to study the pathogenesis and therapeutics of Alzheimer’s disease (AD); however, the molecular mechanisms are not completely understood.ObjectiveThis study aimed to examine the effects of the 5-month administr...

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Principais autores:	Bo Liu, Di Cui, Jie Liu, Jing-Shan Shi
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2024-08-01
סדרה:	Frontiers in Pharmacology
נושאים:	RNA-seq analysis aged SAMP8 mouse Alzheimer’s disease formononetin ingenuity pathway analysis
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1440515/full
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