Impact of reduced robustness settings on the necessity for proton therapy treatment plan adaptation in head-and-neck cancer patients

Background and purpose: Robust optimization mitigates the effects of range and setup uncertainties in intensity–modulated proton therapy (IMPT) through robustness settings. However, it increases the dose to organs-at-risk (OARs). This study investigated how reducing range robustness (RR) and setup r...

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Autors principals:	Brian Zapien-Campos, Dirk Wagenaar, Tim Franssen, Hans Verbeek, Stefan Both, Peter Dendooven
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-03-01
Col·lecció:	Physics and Imaging in Radiation Oncology
Matèries:	Robustness settings Head-and-neck cancer Intensity modulated proton therapy Adaptive proton therapy
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2405631626000631
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