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A Systematic Review and Meta-Analysis on the Number of Adjuvant Temozolomide Cycles in Newly Diagnosed Glioblastoma

BackgroundIn newly diagnosed glioblastoma, radiation with concurrent and adjuvant (six cycles) temozolomide (TMZ) is the established standard of postsurgical care. However, the benefit of extending adjuvant TMZ therapy beyond six cycles has remained unknown.MethodsWe searched PubMed, Web of Science,...

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Principais autores: Fahimeh Attarian, Farzad Taghizadeh-Hesary, Azar Fanipakdel, Seyed Alireza Javadinia, Pejman Porouhan, Babak PeyroShabany, Danial Fazilat-Panah
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-11-01
coleção:Frontiers in Oncology
Assuntos:
adjuvant
extended chemotherapy
glioblastoma
temozolomide
treatment duration
The Stupp protocol
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2021.779491/full
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