Hypomorphic human SEL1L and HRD1 variants uncouple multilayered ER-associated degradation machinery
The suppressor of lin-12-like–HMG-CoA reductase degradation 1 (SEL1L-HRD1) complex of the endoplasmic reticulum–associated degradation (ERAD) machinery is a key cellular proteostasis pathway. Although previous studies have shown ERAD as promoting the development and maintenance of many cell types in...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Clinical Investigation
2024-01-01
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| Saila: | The Journal of Clinical Investigation |
| Sarrera elektronikoa: | https://doi.org/10.1172/JCI175448 |
| Etiketak: |
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