Rare X-linked variants carry predominantly male risk in autism, Tourette syndrome, and ADHD

Abstract Autism spectrum disorder (ASD), Tourette syndrome (TS), and attention-deficit/hyperactivity disorder (ADHD) display strong male sex bias, due to a combination of genetic and biological factors, as well as selective ascertainment. While the hemizygous nature of chromosome X (Chr X) in males...

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Auteurs principaux:	Sheng Wang, Belinda Wang, Vanessa Drury, Sam Drake, Nawei Sun, Hasan Alkhairo, Juan Arbelaez, Clif Duhn, Tourette International Collaborative Genetics (TIC Genetics), Vanessa H. Bal, Kate Langley, Joanna Martin, Pieter J. Hoekstra, Andrea Dietrich, Jinchuan Xing, Gary A. Heiman, Jay A. Tischfield, Thomas V. Fernandez, Michael J. Owen, Michael C. O’Donovan, Anita Thapar, Matthew W. State, A. Jeremy Willsey
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2023-12-01
Collection:	Nature Communications
Accès en ligne:	https://doi.org/10.1038/s41467-023-43776-0
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