In silico validation revealed the role of SCN5A mutations and their genotype–phenotype correlations in Brugada syndrome

Abstract Background Brugada syndrome (BrS) is a rare genetic disease that causes sudden cardiac death (SCD) and arrhythmia. SCN5A pathogenic variants (about 30% of diagnosed patients) are responsible for BrS. Aims Lack of knowledge regarding molecular characteristics and the correlation between geno...

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Detalhes bibliográficos

Principais autores:	Hung Manh Pham, Duy Phuong Dang, Thanh Dat Ta, Thi Phuong Le, Dinh Phong Phan, Hoai An Trinh, Tuan Viet Tran, Thi Lan Anh Luong, Ha Minh Nguyen, The‐Hung Bui, Thinh Huy Tran, Thanh Van Ta, Van‐Khanh Tran
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2023-12-01
coleção:	Molecular Genetics & Genomic Medicine
Assuntos:	Brugada syndrome genotype–phenotype correlation in silico SCN5A mutations
Acesso em linha:	https://doi.org/10.1002/mgg3.2263
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