Induction treatments with and without addition of one dose anthracycline to all-trans retinoid acid and arsenic in pediatric non-high-risk acute promyelocytic leukemia: study protocol for a randomized controlled trial

Abstract Background The treatment of all-trans retinoic acid (ATRA) and arsenical agent has revolutionarily improved the prognosis of acute promyelocytic leukemia (APL) both in adults and children. Nevertheless, coagulation disorder and differentiation syndrome (DS) are the main causes of early deat...

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Autors principals:	Zhong Fan, Xiu-Ya Huang, Dan-Ping Huang, Jie-Si Luo, Jia-Yin Su, Xiao-Li Zhang, Yu Li, Li-Na Wang, Cong Liang, Xue-Qun Luo, Li-Bin Huang, Yan-Lai Tang
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2024-12-01
Col·lecció:	Trials
Matèries:	Acute promyelocytic leukemia Children Arsenic trioxide Realgar-Indigo naturalis formula Chemotherapy
Accés en línia:	https://doi.org/10.1186/s13063-024-08664-y
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