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Astragaloside IV increases PDHA1 in mesenchymal stem cell exosomes to treat myocardial infarction

Abstract Acute myocardial infarction (AMI) is a threat to health, with high morbidity and mortality, posing a challenge to the public health system. This study aimed to explore the efficacy and potential targets of Astragaloside IV (AS-IV) combined with Mesenchymal Stem Cells (MSC)-derived exosomes...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Sha Zhongxin, Chen Zhijie, Du Feng, Guo Mei Qin, Zhong Ya, Hu Jinxin, Wei Zhang, Yu Zhenqiu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2025-07-01
Schriftenreihe:Scientific Reports
Schlagworte:
Astragaloside IV
Myocardial infarction
Mesenchymal stem cells
Exosome
PDHA1
Online-Zugang:https://doi.org/10.1038/s41598-025-08628-5
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