Novel BPI3Vc-vectored surface displayed fusion and hemagglutinin-neuraminidase antigens elicit broadly neutralizing antibodies in cattle

Bovine parainfluenza-3 virus (BPI3V) contributes to Bovine Respiratory Disease Complex, causing severe pneumonia and death in cattle, leading to economic losses. Existing BPI3V commercial vaccines, based on genotype A strains, confer protection against some, but not all, genotype A strains and induc...

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Autors principals:	Huldah Sang, Tae Kim, Rakshith Kumar, Jayden McCall, Aloysius Abraham, Tsvetoslav Koynarski, Michelle Zajac, Karim W. Abdelsalam, Daniela Hernandez Muguiro, Katherine Bauer, Brandon L. Plattner, Waithaka Mwangi
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-02-01
Col·lecció:	Frontiers in Immunology
Matèries:	antigen surface display bovine parainfluenza-3 virus broadly neutralizing antibody efficacy mucosal antibody robust
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1702440/full
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