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Inactivation of Ymr1, Sjl2/3 phosphatases promotes stress resistance and longevity in wild type and Ras2G19V yeast

In Saccharomyces cerevisiae, RAt Sarcoma (Ras) activity plays a central role in mediating the effect of glucose in decreasing stress resistance and longevity, with constitutive Ras activation mutations promoting cell growth and oncogenesis. Here, we used transposon mutagenesis in yeast to identify s...

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Ngā kaituhi matua: M.G. Mirisola, V.D. Longo
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2024-04-01
Rangatū:Biomedical Journal
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2319417023001312
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