Systematic Review of Human and Animal Studies Examining the Efficacy and Safety of N-Acetylcysteine (NAC) and N-Acetylcysteine Amide (NACA) in Traumatic Brain Injury: Impact on Neurofunctional Outcome and Biomarkers of Oxidative Stress and Inflammation

BackgroundNo new therapies for traumatic brain injury (TBI) have been officially translated into current practice. At the tissue and cellular level, both inflammatory and oxidative processes may be exacerbated post-injury and contribute to further brain damage. N-acetylcysteine (NAC) has the potenti...

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Principais autores:	Junaid Bhatti, Barto Nascimento, Umbreen Akhtar, Shawn G. Rhind, Homer Tien, Avery Nathens, Luis Teodoro da Luz
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2018-01-01
סדרה:	Frontiers in Neurology
נושאים:	N-acetylcysteine N-acetylcysteine amide traumatic brain injury neurofunctional outcome animal models oxidative stress
גישה מקוונת:	http://journal.frontiersin.org/article/10.3389/fneur.2017.00744/full
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