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Actomyosin organelle functions of SPIRE actin nucleators precede animal evolution

Abstract An important question in cell biology is how cytoskeletal proteins evolved and drove the development of novel structures and functions. Here we address the origin of SPIRE actin nucleators. Mammalian SPIREs work with RAB GTPases, formin (FMN)-subgroup actin assembly proteins and class-5 myo...

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Principais autores: Martin Kollmar, Tobias Welz, Aishwarya Ravi, Thomas Kaufmann, Noura Alzahofi, Klas Hatje, Asmahan Alghamdi, Jiyu Kim, Deborah A. Briggs, Annette Samol-Wolf, Olena Pylypenko, Alistair N. Hume, Pawel Burkhardt, Jan Faix, Eugen Kerkhoff
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2024-07-01
Series:Communications Biology
Acceso en liña:https://doi.org/10.1038/s42003-024-06458-1
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