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Widespread Inhibition of Posttranscriptional Splicing Shapes the Cellular Transcriptome following Heat Shock

During heat shock and other proteotoxic stresses, cells regulate multiple steps in gene expression in order to globally repress protein synthesis and selectively upregulate stress response proteins. Splicing of several mRNAs is known to be inhibited during heat stress, often meditated by SRp38, but...

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Bibliografske podrobnosti
Principais autores: Reut Shalgi, Jessica A. Hurt, Susan Lindquist, Christopher B. Burge
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2014-06-01
Serija:Cell Reports
Online dostop:http://www.sciencedirect.com/science/article/pii/S2211124714003465
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