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Assessment of corneal nerve regeneration after axotomy in a compartmentalized microfluidic chip model with automated 3D high resolution live-imaging

IntroductionDamage to the corneal nerves can result in discomfort and chronic pain, profoundly impacting the quality of life of patients. Development of novel in vitro method is crucial to better understand corneal nerve regeneration and to find new treatments for the patients. Existing in vitro mod...

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Main Authors: Noémie Bonneau, Anaïs Potey, Frédéric Blond, Camille Guerin, Christophe Baudouin, Jean-Michel Peyrin, Françoise Brignole-Baudouin, Annabelle Réaux-Le Goazigo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
axotomy
corneal neurons
pain
nerve regeneration
microfluidic
compartmentalized culture
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2024.1417653/full
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