Chemical Variations on the p53 Reactivation Theme
Among the tumor suppressor genes, p53 is one of the most studied. It is widely regarded as the “guardian of the genome”, playing a major role in carcinogenesis. In fact, direct inactivation of the TP53 gene occurs in more than 50% of malignancies, and in tumors that retain wild-type p53 status, its...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI AG
2016-05-01
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| Серии: | Pharmaceuticals |
| Предметы: | |
| Online-ссылка: | http://www.mdpi.com/1424-8247/9/2/25 |
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