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Expression of progranulin (GP88) protein appears as an independent prognostic factor for clinical progression in high-risk prostate cancer patients

Abstract Prostate cancer (PCa), the second most common cancer, is still a major cause of morbidity and mortality among men worldwide. A particularly aggressive group of PCa, where prognostic biomarkers are still needed, are clinically defined high-risk PCa. We had previously shown that the survival...

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Uloženo v:
Hlavní autoři: Renata Dubrovska, Markus Eckstein, Rudolf Jung, Charis Kalogirou, Burkhard Kneitz, Martin Spahn, Marianna Kruithof-de Julio, Ginette Serrero, Binbin Yue, Carol Geppert, Robert Stöhr, Arndt Hartmann, Bernd Wullich, Verena Lieb, Helge Taubert, Sven Wach
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2026-06-01
Edice:Scientific Reports
Témata:
Prostate cancer
Progranulin
GP88
Immunohistochemistry
Protein expression
Clinical progression
On-line přístup:https://doi.org/10.1038/s41598-026-52197-0
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