Mitochondrial ubiquinone–mediated longevity is marked by reduced cytoplasmic mRNA translation
This study uses polysomal RNA sequencing to show that the translational efficiency of specific mRNA changes in long-lived Caenorhabditis elegans with reduced ubiquinone synthesis. Mutations in the clk-1 gene impair mitochondrial ubiquinone biosynthesis and extend the lifespan in Caenorhabditis elega...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Life Science Alliance LLC
2018-10-01
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| coleção: | Life Science Alliance |
| Acesso em linha: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.201800082 |
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