Copper-Induced Neurodegenerative Disorders and Therapeutic Potential of Curcumin-Loaded Nanoemulsion

Copper accumulation in neurons induces oxidative stress, disrupts mitochondrial activity, and accelerates neuronal death, which is central to the pathophysiology of neurodegenerative diseases like Wilson disease. Standard treatments for copper toxicity, such as D-penicillamine, trientine, and chloro...

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Bibliografiske detaljer
Main Authors: Govind Hake, Akshada Mhaske, Rahul Shukla, Swaran Jeet Singh Flora
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-01-01
Serier:Toxics
Fag:
copper toxicity
Wilson’s disease
mitochondrial oxidative stress
chelation therapy
neurotoxicity
herbal molecules
Online adgang:https://www.mdpi.com/2305-6304/13/2/108
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