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Dual-Target Insight into Drug Discovery from Natural Products as Modulators of GLP-1 and the TXNIP–Thioredoxin Antioxidant System in Metabolic Syndrome

Metabolic Syndrome (MetS), a cluster of interconnected metabolic abnormalities, poses a growing global health burden. A well-established therapeutic target for the diseases is the incretin hormone glucagon-like peptide-1 (GLP-1); however, synthetic agonists have drawbacks such as expense, injectable...

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Principais autores: Peter Chinedu Agu, Appolonia Fulgence Yudas, Jun Lu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-11-01
coleção:Antioxidants
Assuntos:
GLP-1
TXNIP
thioredoxin
natural products
antioxidant
metabolic syndrome
Acesso em linha:https://www.mdpi.com/2076-3921/14/11/1364
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