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Evaluation of a steroid delivery system to mitigate the severity of proliferative vitreoretinopathy in a minipig model

PurposeTo investigate the efficacy of liposomal prednisolone phosphate to mitigate the severity of proliferative vitreoretinopathy (PVR) in a minipig model of PVR.MethodsA total of 18 eyes of 9 minipigs underwent PVR induction surgically. Eyes were randomized equally into three groups: intravitreal...

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Principais autores: Chee Wai Wong, Ning Cheung, James S. Howden, Joanna Marie Fianza Busoy, Shaun Sim, Joshua Lim, Candice Ho, Amutha Barathi Veluchamy, Gert Storm, Tina T. Wong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-11-01
coleção:Frontiers in Ophthalmology
Assuntos:
proliferative vitreoretinopathy
liposome
drug delivery
retinal detachment
animal model
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fopht.2023.1222689/full
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