HIF-1α Protects Granulosa Cells From Hypoxia-Induced Apoptosis During Follicular Development by Inducing Autophagy

Owing to the avascular structure of the ovarian follicle, proliferation of granulosa cells (GCs) and development of follicles occur under hypoxia, which is obviously different from the cell survival requirements of most mammalian cells. We hypothesized that autophagy may exert an inhibitory effect o...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Zonghao Tang, Renfeng Xu, Zhenghong Zhang, Congjian Shi, Yan Zhang, Hongqin Yang, Qingqiang Lin, Yiping Liu, Fengping Lin, Baorong Geng, Zhengchao Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-01-01
Colecção:	Frontiers in Cell and Developmental Biology
Assuntos:	hypoxia autophagy apoptosis granulosa cell follicular development
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcell.2021.631016/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!