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Short-Interval Sequential CAR-T Cell Infusion May Enhance Prior CAR-T Cell Expansion to Augment Anti-Lymphoma Response in B-NHL

Chimeric antigen receptor (CAR)-T cell therapy emerges as a new treatment for refractory or relapsed (r/r) B-cell non-Hodgkin lymphoma (B-NHL); however, the overall response rate (ORR) of which in the B-NHL patients is much lower compared to the patients with r/r B acute lymphoblastic leukemia (B-AL...

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Principais autores: Yuan Meng, Biping Deng, Luan Rong, Chuo Li, Weiliang Song, Zhuojun Ling, Jinlong Xu, Jiajia Duan, Zelin Wang, Alex H. Chang, Xiaoming Feng, Xiujuan Xiong, Xiaoli Chen, Jing Pan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-06-01
coleção:Frontiers in Oncology
Assuntos:
B-NHL
CAR-T
CD19
CD22
CD20
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2021.640166/full
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