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Autophagy and mitophagy in dermatological disease: a comprehensive review from molecular pathways to therapeutic frontiers

Abstract Autophagy – the cell’s built-in recycling and quality-control programme – touches every layer of cutaneous biology. In keratinocytes it sculpts the cornified envelope; in melanocytes it balances pigment synthesis and oxidative stress; in immune and appendageal cells it fine-tunes defence, r...

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Kaydedildi:
Asıl Yazarlar: Luca D’Ambrosio, Maria Elisabetta Greco, Maurizio Forte, Daniele Vecchio, Sonia Schiavon, Flavio Di Nonno, Shazia Tahir, Vittorio Picchio, Claudia Cozzolino, Gianmarco Sarto, Marco Bernardi, Luigi Spadafora, Beatrice Simeone, Mattia Vinciguerra, Sebastiano Sciarretta, Giacomo Frati, Ernesto Greco, Concetta Potenza, Ilaria Proietti, Jacopo Morroni, Elisa Dietrich, Leonardo Schirone
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2025-12-01
Seri Bilgileri:Biology Direct
Konular:
Autophagy
Mitophagy
Skin disorders
Dermatological disease
Skin homeostasis
Immunodermatology
Online Erişim:https://doi.org/10.1186/s13062-025-00703-1
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