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Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres.

The catalytic subunit of yeast telomerase, Est2p, is a telomere associated throughout most of the cell cycle, while the Est1p subunit binds only in late S/G2 phase, the time of telomerase action. Est2p binding in G1/early S phase requires a specific interaction between telomerase RNA (TLC1) and Ku80...

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Détails bibliographiques
Auteurs principaux: Angela Chan, Jean-Baptiste Boulé, Virginia A Zakian
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2008-10-01
Collection:PLoS Genetics
Accès en ligne:http://europepmc.org/articles/PMC2567097?pdf=render
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