Valosin-Containing Protein Contributes to Plexiform Neurofibroma Formation and Represents a Novel Therapeutic Target

Neurofibromatosis type 1 (NF1) patients are predisposed to develop plexiform neurofibromas (PNFs). By cross-comparison of RNA sequencing and RUNX1-CHIP sequencing data on mouse PNFs, we found that transcripts encoding the NF1-interacting p97/valosin-containing protein (VCP) gene are overexpressed in...

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Главные авторы:	Lalitha Gopalan, Youjin Na, Liang Hu, Ashley Hall, Mi-Ok Kim, Eva Dombi, Sara Szabo, Nancy Ratner, Gang Huang, Jianqiang Wu
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2026-05-01
Серии:	Cells
Предметы:	neurofibromin plexiform neurofibroma Schwann cell p97/VCP CB-5083 PD0325901
Online-ссылка:	https://www.mdpi.com/2073-4409/15/9/848
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