Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome
Ubiquitin-dependent proteolysis can initiate at ribosomes for myriad reasons including misfolding of a nascent chain or stalling of the ribosome during translation of mRNA. Clearance of a stalled complex is required to recycle the ribosome for future use. Here we show that the ubiquitin (Ub) pathway...
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| Principais autores: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
eLife Sciences Publications Ltd
2013-01-01
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| 叢編: | eLife |
| 主題: | |
| 在線閱讀: | https://elifesciences.org/articles/00308 |
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