Hantaan virus-induced elevation of plasma osteoprotegerin and its clinical implications in hemorrhagic fever with renal syndrome

Objectives: The bleeding tendency is a hallmark of hemorrhagic fever with renal syndrome (HFRS) after Hantaan virus (HTNV) infection. Growing reports indicate the importance of osteoprotegerin (OPG) in vascular homeostasis, implying OPG might be involved in the pathogenesis of coagulopathy in patien...

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Autores principales:	Kang Tang, Yusi Zhang, Chunmei Zhang, Haifeng Hu, Ran Zhuang, Boquan Jin, Yun Zhang, Ying Ma
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2023-01-01
Colección:	International Journal of Infectious Diseases
Materias:	Hemorrhagic fever with renal syndrome Hantaan virus Osteoprotegerin Endothelium dysfunction Inflammatory responses Pathological coagulopathy
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S1201971222005914
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