Role of Glutamatergic Excitotoxicity in Neuromyelitis Optica Spectrum Disorders

Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disorder mediated by immune-humoral responses directed against central nervous system (CNS) antigens. Most patients are positive for specific immunoglobulin G (IgG) auto-antibodies for aquaporin-4 (AQP4), a water channel present in as...

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Principais autores:	Ana Paula Bornes da Silva, Débora Guerini Souza, Diogo Onofre Souza, Denise Cantarelli Machado, Douglas Kazutoshi Sato
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-04-01
Colecção:	Frontiers in Cellular Neuroscience
Assuntos:	neuromyelitis optica spectrum disorders aquaporin-4 antibody astrocytes glutamate excitotoxicity
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fncel.2019.00142/full
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