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Induction of input-specific spine shrinkage on dendrites of rodent hippocampal CA1 neurons using two-photon glutamate uncaging

Summary: Shrinkage and loss of dendritic spines are vital components of the neuronal plasticity that supports learning. To investigate the mechanisms of spine shrinkage and loss, Oh and colleagues established a two-photon glutamate uncaging protocol that reliably induces input-specific spine shrinka...

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Autors principals: Jinyoung Jang, Margarita Anisimova, Won Chan Oh, Karen Zito
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021-12-01
Col·lecció:STAR Protocols
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2666166721007024
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