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Redesigning CAR therapy to tackle immune effector cell-associated hematotoxicity

Abstract Although recognized, the field has yet to fully explore the mechanisms and solutions to Immune effector Cell-Associated Hematotoxicity (ICAHT) - a major contributor to long term morbidity and mortality following CAR therapy. About 20–40% of the patients develop ICAHT of grade 3 or above, wi...

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Hlavní autoři: Muhamad Shafi Kooniyil, Pranav Thomas Alex, Muthuganesh Muthuvel, Alok Srivastava, Sunil Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer 2026-04-01
Edice:Annals of Hematology
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On-line přístup:https://doi.org/10.1007/s00277-026-06982-6
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