High-level expression of leghemoglobin in Kluyveromyces marxianus by remodeling the heme metabolism pathway

Soy leghemoglobin, when bound to heme, imparts a meat-like color and flavor and can serve as a substitute for animal-derived proteins. Enhancing cellular heme synthesis improves the recombinant expression of leghemoglobin in yeast. To achieve high-level expression of leghemoglobin A (LBA) in Kluyver...

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Autori principali:	Tian Tian, Xinwei Wu, Pingping Wu, Xinyi Lu, Qi Wang, Yifan Lin, Canjie Liu, Jungang Zhou, Yao Yu, Hong Lu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2024-01-01
Serie:	Frontiers in Bioengineering and Biotechnology
Soggetti:	Kluyveromyces marxianus leghemoglobin heme biosynthesis yeast artificial chromosomes high-level expression
Accesso online:	https://www.frontiersin.org/articles/10.3389/fbioe.2023.1329016/full
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