In vivo confocal microscopy provides evidence of corneal nerve damage and basal tear film reduction in patients treated with oral isotretinoin

Abstract Background Isotretinoin is a vitamin A derivative used as a first-line treatment for moderate to severe acne. One of its most frequent side effects is dry eye disease (DED), in which tear film instability and neurosensory abnormalities play an etiologic role. The purpose of this research wa...

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Bibliografische Detailangaben

Hauptverfasser:	Alberto Barros, Javier Lozano-Sanroma, Juan Queiruga-Piñeiro, Luis Fernández-Vega-Cueto, Cristina Sánchez-Fernández, Jesús Merayo-Lloves, Ignacio Alcalde
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-05-01
Schriftenreihe:	Journal of Translational Medicine
Schlagworte:	Corneal nerves Isotretinoin In vivo confocal microscopy Ocular surface disease
Online-Zugang:	https://doi.org/10.1186/s12967-025-06577-1
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