Risk score modeling of multiple gene to gene interactions using aggregated-multifactor dimensionality reduction

<p>Abstract</p> <p>Background</p> <p>Multifactor Dimensionality Reduction (MDR) has been widely applied to detect gene-gene (GxG) interactions associated with complex diseases. Existing MDR methods summarize disease risk by a dichotomous predisposing model (high-risk/low-risk) from one optimal GxG i...

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Egile Nagusiak:	Dai Hongying, Charnigo Richard J, Becker Mara L, Leeder J, Motsinger-Reif Alison A
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2013-01-01
Saila:	BioData Mining
Gaiak:	A-MDR Epistasis enriched risk score Epistasis enriched gene network pRR pOR pChi
Sarrera elektronikoa:	http://www.biodatamining.org/content/6/1/1
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