Senescent Tumor Cells in the Peritoneal Carcinomatosis Drive Immunosenescence in the Tumor Microenvironment

More than half of all patients with colorectal cancer (CRC) develop distant metastasis and, depending on the local stage of the primary tumor, up to 48% of patients present peritoneal carcinomatosis (PC). PC is often considered as a widespread metastatic disease, which is almost resistant to current...

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Principais autores:	Heidi Braumüller, Bernhard Mauerer, Christopher Berlin, Dorothea Plundrich, Patrick Marbach, Pierre Cauchy, Claudia Laessle, Esther Biesel, Philipp Anton Holzner, Rebecca Kesselring
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2022-06-01
Serija:	Frontiers in Immunology
Teme:	Colorectal cancer peritoneal carcinomatosis tumor cell senescence T cell senescence stem cell phenotype
Online dostop:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.908449/full
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