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Dorsal root ganglion neuromodulation restores accumbal gate to inhibit mechanical allodynia

Abstract Background Mechanical allodynia refers to a hypersensitive status in response to innoxious stimuli caused by neuropathic pain. A therapeutic strategy to reverse the sensory impairment is neuromodulation treatment selectively targeting the dorsal root ganglion. However, the supra-spinal mech...

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Principais autores: Xuelian Li, Hongyi Wang, Jiahui Ma, Zhenxing Li, Kuankuan Li, Xuebin Yan, Dong Huang, Xing Liu, Yuzhao Huang, Rong Hu, Haocheng Zhou
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-01-01
Serier:The Journal of Headache and Pain
Fag:
Neuropathic pain
Noxious
Mechanical allodynia
Dorsal root ganglion
Neuromodulation
Spinal
Online adgang:https://doi.org/10.1186/s10194-026-02279-1
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