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N-terminus of Drosophila melanogaster MSL1 is critical for dosage compensation

The male-specific lethal complex (MSL), which consists of five proteins and two non-coding roX RNAs, is involved in the transcriptional enhancement of X-linked genes to compensate for the sex chromosome monosomy in Drosophila XY males compared with XX females. The MSL1 and MSL2 proteins form the het...

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Principais autores: Valentin Babosha, Natalia Klimenko, Anastasia Revel-Muroz, Evgeniya Tikhonova, Pavel Georgiev, Oksana Maksimenko
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2024-12-01
Serier:eLife
Fag:
sex determination
RNA-protein interaction
MSL complex
transcription factor
MSL2
MSL3
Online adgang:https://elifesciences.org/articles/93241
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